Welcome to Signature Orthopaedics' electronic Instructions for Use archive.

Historic Instructions for Use may be accessed here. Please identify the appropriate Instructions for Use by following the instructions here, then retrieve the desired historic copy from the table below.

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Instruction for Use Jurisdiction Issue Date Revision Language
121-051-003 Soft Tissue Fixation Europe, Australia October 2015 E English
121-051-003 Soft Tissue Fixation Europe, Australia July 2016 F English
121-051-003 Soft Tissue Fixation Europe, Australia January 2017 G English
121-051-003 Soft Tissue Fixation Europe, Australia October 2017 H English
121-051-003 Soft Tissue Fixation Europe, Australia December 2017 I English
121-051-003 Soft Tissue Fixation Europe, Australia January 2018 J English
121-051-003 Soft Tissue Fixation Europe, Australia February 2018 K English
121-051-003 Soft Tissue Fixation Europe, Australia July 2018 L English
121-051-003 Soft Tissue Fixation Europe, Australia September 2018 M English
121-051-003 Soft Tissue Fixation Europe, Australia October 2020 N English
121-051-003 Soft Tissue Fixation Europe, Australia February 2021 O English
121-051-003 Soft Tissue Fixation Europe, Australia May 2021 P English
111-142-004 Hip Systems USA United States June 2016 I English
111-142-004 Hip Systems USA United States October 2016 J English
111-142-004 Hip Systems USA United States June 2017 K English
111-142-004 Hip Systems USA United States March 2018 L English
111-142-004 Hip Systems USA United States May 2018 M English
111-142-004 Hip Systems USA United States May 2018 N English
111-142-004 Hip Systems USA United States May 2018 O English
111-142-004 Hip Systems USA United States September 2018 P English
111-142-004 Hip Systems USA United States October 2018 Q English
111-142-004 Hip Systems USA United States November 2018 R English
111-142-004 Hip Systems USA United States July 2019 S English
111-142-004 Hip Systems USA United States September 2019 T English
111-142-004 Hip Systems USA United States July 2020 Z English
111-142-004 Hip Systems USA United States October 2020 AA English
111-142-004 Hip Systems USA United States February 2021 AB English
111-142-004 Hip Systems USA United States May 2021 AC English
111-142-004 Hip Systems USA United States June 2021 AD English
111-142-004 Hip Systems USA United States August 2021 AE English
111-142-004 Hip Systems USA United States September 2021 AF English
111-142-004 Hip Systems USA United States February 2022 AG English
131-111-001 Spinal Implants Europe, Australia November 2015 I English
131-111-001 Spinal Implants Europe, Australia December 2016 K English
131-111-001 Spinal Implants Europe, Australia December 2016 L English
131-111-001 Spinal Implants Europe, Australia September 2020 P English
131-111-001 Spinal Implants Europe, Australia October 2020 Q English
131-111-001 Spinal Implants Europe, Australia March 2021 S English
131-111-001 Spinal Implants Europe, Australia May 2021 T English
131-111-001 Spinal Implants Europe, Australia May 2021 U English
131-111-001 Spinal Implants Europe, Australia May 2021 W English
131-111-001 Spinal Implants Europe, Australia September 2020 P Deutsche
131-111-001 Spinal Implants Europe, Australia October 2020 Q Deutsche
131-111-001 Spinal Implants Europe, Australia March 2021 S Deutsche
131-111-001 Spinal Implants Europe, Australia May 2021 T Deutsche
131-111-001 Spinal Implants Europe, Australia May 2021 U Deutsche
131-111-001 Spinal Implants Europe, Australia May 2021 W Deutsche
131-111-001 Spinal Implants Europe, Australia Octobre 2020 Q Italian
131-111-001 Spinal Implants Europe, Australia March 2021 S Italian
131-111-001 Spinal Implants Europe, Australia May 2021 T Italian
131-111-001 Spinal Implants Europe, Australia May 2021 U Italian
131-111-001 Spinal Implants Europe, Australia May 2021 W Italian
111-142-002 Hip Systems Europe, Australia June 2015 K Italiano
111-142-002 Hip Systems Europe, Australia January 2016 M English
111-142-002 Hip Systems Europe, Australia January 2016 M Francais
111-142-002 Hip Systems Europe, Australia January 2017 N English
111-142-002 Hip Systems Europe, Australia January 2017 N Francais
111-142-002 Hip Systems Europe, Australia January 2017 N Italiano
111-142-002 Hip Systems Europe, Australia September 2018 Q English
111-142-002 Hip Systems Europe, Australia September 2018 Q Francais
111-142-002 Hip Systems Europe, Australia September 2018 Q Italiano
111-142-002 Hip Systems Europe, Australia November 2019 S English
111-142-002 Hip Systems Europe, Australia November 2019 S Francais
111-142-002 Hip Systems Europe, Australia November 2019 S Italiano
121-07-0100 Genius Total Knee Systems United States February 2017 B English
121-07-0100 Genius Total Knee Systems United States June 2017 C English
121-07-0100 Genius Total Knee Systems United States March 2018 D English
121-07-0100 Genius Total Knee Systems United States February 2019 G English
121-07-0100 Genius Total Knee Systems United States Octobre 2020 H English
W31-04-0002 Brisbane and Gladstone ALIF Cages United States October 2016 A English
W31-04-0002 Brisbane and Gladstone ALIF Cages United States June 2017 B English
W31-04-0002 Brisbane and Gladstone ALIF Cages United States September 2018 C English
W31-062-001 Arlington PLIF/TLIF Cage United States September 2016 A English
W31-062-001 Arlington PLIF/TLIF Cage United States June 2017 B English
W31-062-001 Arlington PLIF/TLIF Cage United States September 2017 C English
W31-062-001 Arlington PLIF/TLIF Cage United States September 2018 D English
W31-091-004 Anterior Lumbar Plate IFU United States December 2016 A English
W31-091-004 Anterior Lumbar Plate IFU United States April 2017 B English
W31-091-004 Anterior Lumbar Plate IFU United States September 2020 C English
191-051-500 Osteosynthesis Plate System Europe, Australia March 2015 B English
191-051-500 Osteosynthesis Plate System Europe, Australia September 2017 C English
191-051-500 Osteosynthesis Plate System Europe, Australia September 2017 D English
191-051-500 Osteosynthesis Plate System Europe, Australia March 2018 E English
191-051-500 Osteosynthesis Plate System Europe, Australia September 2018 F English
191-07-0901 Foot and Ankle Implants Europe, Australia February 2016 D English
191-07-0901 Foot and Ankle Implants Europe, Australia December 2017 E English
191-07-0901 Foot and Ankle Implants Europe, Australia September 2018 F English
121-132-016 Active Knee System IFU Europe, Australia November 2016 A English
121-132-016 Active Knee System IFU Europe, Australia March 2017 B English
121-132-016 Active Knee System IFU Europe, Australia September 2018 C English
121-132-016 Active Knee System IFU Europe, Australia July 2020 D English
121-132-016 Active Knee System IFU Europe, Australia October 2020 E English
121-132-016 Active Knee System IFU Europe, Australia March 2021 H English
121-200-001_World_Knee_System_IFU United States February 2017 A English
121-200-001_World_Knee_System_IFU United States November 2019 B English
121-200-001_World_Knee_System_IFU United States September 2018 D English
111-37-9005 Fusion Taper System IFU United States Jan 2018 A English
131-13-0108 Pedicle Screw IFU Europe, Australia, United States March 2018 A English
131-13-0108 Pedicle Screw IFU Europe, Australia, United States October 2018 C English
W31-161-004 Anterior Cervical Plate IFU United States April 2018 A English
W31-161-004 Anterior Cervical Plate IFU United States December 2018 C English
111-072-357 C2 Base Hole Cover Europe August 2016 A English
111-072-357 C2 Base Hole Cover Europe September 2018 B English
192-111-001 Drill Bits Europe, Australia October 2015 E English
192-111-001 Drill Bits Europe, Australia September 2018 G English
911-012-100 Knee Systems Europe July 2016 B English
911-012-100 Knee Systems Europe January 2017 C English
911-012-100 Knee Systems Europe January 2017 C Francais
191-332-002 Augment Range Australia April 2019 B English
191-332-002 Augment Range Australia January 2020 C English
911-012-100 I Knee Total Knee System Europe September 2018 D English
911-012-100 I Knee Total Knee System Europe September 2020 E English
911-012-100 I Knee Total Knee System Europe September 2018 D Francais
911-012-100 I Knee Total Knee System Europe September 2020 E Francais
192-340-001 K-Wires and Steinmann Pins IFU Europe September 2019 A English
192-340-001 K-Wires and Steinmann Pins IFU Europe October 2020 B English
192-340-001 K-Wires and Steinmann Pins IFU Europe June 2021 C English
132-021-700 Curvy System IFU Europe August 2019 F English
132-021-700 Curvy System IFU Europe June 2021 G English